주의사항은 이용자 전원 예외 없이 꼭 지켜 주셔야 하는 규칙이며 , 만약 본인의 귀책사유로 인해서 규정 하고 있는 주의사항을 어기실 경우 그로 인해 발생하는 모든 사건에 대한 피해와 보상을 청구 당하실 수 있다는 사실을 강조 드립니다.
Trichothiodystrophy, frequently known as TTD, is actually a rare inherited problem that has an effect on lots of areas of your body. The hallmark of this issue is hair that is sparse and easily damaged. [from MedlinePlus Genetics]
Cholesterol is a waxy, Excess fat-like compound that is made in your body and received from foods that originate from animals; it aids in several functions of the body but could become dangerous in extreme amounts. As entire LCAT deficiency progresses, the corneal cloudiness worsens and can lead to severely impaired vision.
The indications and symptoms of trichothiodystrophy range extensively. Delicate instances may perhaps entail only the hair. Far more severe situations also cause delayed growth, significant intellectual incapacity, and recurrent bacterial infections; severely affected folks may well endure only into infancy or early childhood.
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Men and women with milder disorder can survive into adulthood. People with any volume of severity in the condition might have episodes of far more significant hemolysis, referred to as hemolytic crises, which can be brought on by bacterial or viral infections.
The affected bones may well themselves be unpleasant, or agony could be a result of arthritis in close by joints. Arthritis final results once the distortion of bones, notably weight-bearing bones inside the legs, will cause extra use and tear over the joints. Arthritis most often affects the knees and hips in people with this ailment.
Other features of trichothiodystrophy can incorporate dry, scaly pores and skin (ichthyosis); abnormalities from the fingernails and toenails; clouding with the lens in both eyes from beginning (congenital cataracts); very poor coordination; and skeletal abnormalities together with degeneration of each hips at an early age.
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Scalp hair may be lighter in coloration than expected and is also fragile and simply damaged. Afflicted individuals usually are unable to develop hair for a longer time than the usual several inches. The eyebrows, eyelashes, and other physique hair could possibly be sparse as well. As time passes, the hair difficulties can continue to be steady or development to finish scalp hair reduction (alopecia) plus a lower in overall body hair.
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Crigler-Najjar syndrome is a critical situation characterised by higher amounts of a harmful substance named bilirubin within the blood (hyperbilirubinemia). Bilirubin is developed when pink blood cells are damaged down. This substance is removed from your body only soon after it undergoes a chemical response from the liver, which converts the harmful type of bilirubin (named unconjugated bilirubin) to your nontoxic sort identified as conjugated bilirubin.
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